Heat-induced bone injury

Tremperature threshold levels for heat-induced bone injury: A vital-microscopic study in the rabbit

Eriksson and Albrektsson 1983
  • Critical temperature is to be around 56° because alkaline phosphate denatured at this temperature level.
  • Hard tissue changes after heating in the range of 47° to 50  c.
  • The heating was performed about 10 weeks liter chamber insertion. 
  • Acute effects. A hyperemia was noted during heating. This increase in blood flow velocity was when the temperature was raised to 40* to 41° C higher. 
  • Long-term effects. The following changes in vessels, fat cells, and bone occurred as long-term effects. 
  • Daring further observation period of 40 to 50 days, only minor vascular changes such as a slight reorientation of the vessels occurred. 
  • Pat cells. Fat cell resorption usually started 2 days after heating with changes in the appearance of cells and a darkening of their color. 
  • An observation period of 30 to 40 days, about 30% of the bone was resorbed
  • The increased blood flow was observed at a temperature of 40 c to 41° C.
  •  In the present study no permeability was observed. 
  • observation that a circulatory arrest was noted in some minor vessels after heating to ^0° C may imply that the threshold level for vascular survival is readied. at this temperature. 
  • Heating to of 60° C or more resulted in 2 permanent cessation of blood flow and an obvious bone tissue necrosis 
  • no signs of tissue recovery even over follow-up periods of 1 year. 
  • This study indicates that bone tissue is sensitive to heating at the level of 47” C in 1 min